Sail Central America from Atlantic to Pacific
View natural beauty and an engineering marvel across the Panama Canal
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Featured Panama Canal Cruises
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12 Night Panama Canal with Costa Rica & Caribbean
Emerald Princess
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- Oranjestad, Aruba
- Willemstad, Curacao
- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Puerto Limon, Costa Rica
- George Town, Grand Cayman
Sailing Dates:- March 2025
interior from$1,248$104pernightoceanview from$1,473$123pernightbalcony from$2,686$224pernightsuite from$4,239$353pernightInterior from $1,248($104pernight)4 rating out of 5 (1,211 reviews) -
8 Night Panama Canal
Carnival Miracle
Departing from: Tampa, FloridaPorts of Call:- Puerto Limon, Costa Rica
- Colon, Panama
- George Town, Grand Cayman
Sailing Dates:- January 2026
- March 2026
interior from$1,074$134pernightoceanview from$1,224$153pernightbalcony from$1,484$186pernightsuite from$2,804$351pernightInterior from $1,074($134pernight)4 rating out of 5 (2,764 reviews) -
16 Night Panama Canal Carnival Journeys - Eastbound
Carnival Spirit
Departing from: Seattle, WashingtonPorts of Call:- Cabo San Lucas, Mexico
- Puntarenas, Costa Rica
- Panama Canal Full Transit
- Cartagena, Colombia
- New Orleans, Louisiana
Sailing Dates:- October 2025
interior from$1,113$70pernightoceanview from$1,433$90pernightbalcony from$1,703$106pernightsuite fromCall for availabilityInterior from $1,113($70pernight)4 rating out of 5 (985 reviews) -
11 Night Panama Canal: Mexico Costa Rica & Belize
Norwegian Gem - OPEN BAR!
Departing from: Miami, FloridaPorts of Call:- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Sailing Dates:- January 2025
interior fromCall for availabilityoceanview fromCall for availabilitybalcony fromCall for availabilitysuite from$5,141$467pernightSuite from $5,141($467pernight)3.8 rating out of 5 (2,498 reviews) -
11 Night Panama Canal: Cartagena & Cozumel
Norwegian Jade - OPEN BAR!
Departing from: Tampa, FloridaPorts of Call:- Key West, Florida
- Cozumel, Mexico
- George Town, Grand Cayman
- Ocho Rios, Jamaica
- Cartagena, Colombia
- Colon, Panama
- Puerto Limon, Costa Rica
- Panama Canal Full Transit
- Panama City, Panama
Sailing Dates:- January 2025
interior from$901$82pernightoceanview fromCall for availabilitybalcony from$1,821$166pernightsuite from$2,221$202pernightRewards & Bonus Offers:Interior from $901($82pernight)3.9 rating out of 5 (1,411 reviews) -
12 Night Panama Canal with Costa Rica & Caribbean
Emerald Princess
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- Kralendijk, Bonaire
- Willemstad, Curacao
- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Puerto Limon, Costa Rica
- George Town, Grand Cayman
Sailing Dates:- February 2025
interior from$1,098$92pernightoceanview from$1,196$100pernightbalcony from$2,748$229pernightsuite from$3,463$289pernightInterior from $1,098($92pernight)4 rating out of 5 (1,211 reviews) -
12 Night Panama Canal with Costa Rica & Caribbean
Caribbean Princess
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- George Town, Grand Cayman
- Falmouth, Jamaica
- Puerto Limon, Costa Rica
- Panama Canal (Partial Transit)
- Colon, Panama
- Oranjestad, Aruba
- Willemstad, Curacao
Sailing Dates:- November 2025
- February 2026
interior from$1,389$116pernightoceanview from$1,428$119pernightbalcony from$1,989$166pernightsuite from$2,399$200pernightInterior from $1,389($116pernight)3.9 rating out of 5 (1,897 reviews) -
16 Night Panama Canal Westward
Serenade of the Seas
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- George Town, Grand Cayman
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Full Transit
- Puerto Quetzal, Guatemala
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Pedro (Los Angeles), California
Sailing Dates:- April 2025
interior from$1,740$109pernightoceanview from$1,971$123pernightbalcony from$3,211$201pernightsuite from$8,943$559pernightWas $2,514 – Save up to 31%Interior from $1,740($109pernight)4.1 rating out of 5 (1,806 reviews) -
15 Night Panama Canal - Westbound
Radiance of the Seas
Departing from: Tampa, FloridaPorts of Call:- George Town, Grand Cayman
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Full Transit
- Puerto Quetzal, Guatemala
- Puerto Vallarta, Mexico
- Los Angeles, California
Sailing Dates:- April 2025
interior from$1,607$107pernightoceanview from$1,815$121pernightbalcony from$3,389$226pernightsuite fromCall for availabilityWas $3,241 – Save up to 50%Interior from $1,607($107pernight)4.2 rating out of 5 (1,273 reviews)
Discount Panama Canal Cruises
Search Panama Canal Cruises
- Azamara Cruises from $3,789
- Celebrity Cruises from $1,647
- Cunard from $1,599
- Holland America Line from $704
- Norwegian Cruise Line from $901
- Oceania Cruises from $2,999
- Ponant from $5,150
- Princess Cruises from $1,043
- Regent Seven Seas Cruises from $8,499
- Royal Caribbean from $1,360
- Seabourn from $4,249
- Silversea Cruises from $5,800
- Viking Ocean Cruises from $2,999
- Windstar Cruises from $2,445